FAM161B antibody (AA 451-560) (AbBy Fluor® 350)

Catalog No. ABIN896427

This anti-FAM161B antibody is a Rabbit Polyclonal antibody detecting FAM161B in IF (cc) and IF (p). Suitable for Rat.

Quick Overview for FAM161B antibody (AA 451-560) (AbBy Fluor® 350) (ABIN896427)

Target: FAM161B (Family with Sequence Similarity 161, Member B (FAM161B))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM161B antibody is conjugated to AbBy Fluor® 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FAM161B Antibody (AbBy Fluor® 350)

Binding Specificity: AA 451-560

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM161B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM161B

Target: FAM161B (Family with Sequence Similarity 161, Member B (FAM161B))

Alternative Name: FAM161B

Background:

Synonyms: C14orf44, Chromosome 14 open reading frame 44, Family with sequence similarity 161, member B, FLJ31697, Hypothetical protein LOC145483, Protein FAM161B, F161B_HUMAN.

Background: FAM161B is a 647 amino acid protein that belongs to the FAM161 family. The gene that encodes FAM161B consists of approximately 16,413 bases and maps to human chromosome 14q24.3. Housing over 700 genes, chromosome 14 comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the Presenilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer?s disease. The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder 1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. An inversion of the long arm of chromosome 14 is thought to be involved in T-cell chronic lymphocytic leukemia (CLL), a cancer that affects T lymphocytes.