Fascin antibody (AA 401-493) (Cy7)

Catalog No. ABIN896783

The Rabbit Polyclonal anti-Fascin antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect Fascin in samples from Mouse.

Quick Overview for Fascin antibody (AA 401-493) (Cy7) (ABIN896783)

Target: Fascin (FSCN1)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fascin antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Fascin Antibody (Cy7)

Binding Specificity: AA 401-493

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Fascin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Fascin

Target: Fascin (FSCN1)

Alternative Name: Fascin

Background:

Synonyms: 55 kDa actin bundling protein, 55 kDa actin-bundling protein, Actin bundling protein, FAN 1, Fscin1, FAN1, Fascin 1, Fascin, Fascin homolog 1 actin bundling protein Strongylocentrotus purpuratus, Fascin homolog 1, Fascin1, FLJ38511, FSCN 1, FSCN1, FSCN1_HUMAN, HSN, p55, Singed Drosophila like sea urchin fascin homolog like, Singed drosophila homolog like, Singed like fascin homolog sea urchin Drosophila, Singed like fascin homolog sea urchin, Singed like protein, Singed-like protein, SNL, Strongylocentrotus purpuratus.

Background: Fascin is a highly conserved actin-bundling protein. Fascin, encoded by the human homolog for sn (hsn) gene, has been localized to microspikes and stress fibers of cultured cells where it is thought to be involved in the formation of microfilament bundles. It is expressed predominantly in dendritic cells. Lymphoid cells, myeloid cells and plasma cells are negative. However, Reed Sternberg cells in Hodgkin?s lymphoma are positive for fascin staining. Epstein-Barr virus may induce expression of fascin in B cells.

Gene ID: 6624