FRMD5 antibody (AA 211-312) (FITC)

Catalog No. ABIN897787

This Rabbit Polyclonal antibody specifically detects FRMD5 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for FRMD5 antibody (AA 211-312) (FITC) (ABIN897787)

Target: FRMD5 (FERM Domain Containing 5 (FRMD5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRMD5 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FRMD5 Antibody (FITC)

Binding Specificity: AA 211-312

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FRMD5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FRMD5

Target: FRMD5 (FERM Domain Containing 5 (FRMD5))

Alternative Name: FRMD5

Background:

Synonyms: FERM domain containing 5, FERM domain-containing protein 5, FLJ41022, FRMD5, FRMD5_HUMAN, MGC14161.

Background: FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. FRMD5 (FERM domain-containing protein 5) is a 570 amino acid single-pass membrane protein that contains one FERM domain and exists as two alternatively spliced isoforms. The gene encoding FRMD5 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Gene ID: 84978