GANP antibody (AA 435-535) (HRP)

Catalog No. ABIN898317

The HRP-conjugated Rabbit Polyclonal anti-GANP antibody (ABIN898317) specifically detects GANP in WB, ELISA, IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for GANP antibody (AA 435-535) (HRP) (ABIN898317)

Target: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GANP antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GANP Antibody (HRP)

Binding Specificity: AA 435-535

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GANP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GANP

Target: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Alternative Name: GANP

Background:

Synonyms: 80 kDa MCM3 associated protein, 80 kDa MCM3-associated protein, Germinal center associated nuclear protein, KIAA0572, MAP80, MCM3 import protein, MCM3 minichromosome maintenance deficient 3 S. cerevisiae associated protein, MCM3 minichromosome maintenance deficient 3 associated protein, MCM3A, MCM3A_HUMAN, MCM3AP, Minichromosome maintenance complex component 3 associated protein, Minichromosome maintenance deficient 3 associated protein, Minichromosome maintenance protein 3 associated protein, Protein GANP.

Background: The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization.

Gene ID: 8888

Pathways: Protein targeting to Nucleus