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Gelsolin antibody (AA 51-150) (AbBy Fluor® 647)

This Rabbit Polyclonal antibody specifically detects Gelsolin in WB, FACS, IF (cc) and IF (p). It exhibits reactivity toward Human and Rat.
Catalog No. ABIN898618

Quick Overview for Gelsolin antibody (AA 51-150) (AbBy Fluor® 647) (ABIN898618)

Target

See all Gelsolin (GSN) Antibodies
Gelsolin (GSN)

Reactivity

  • 125
  • 38
  • 33
  • 12
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Rat

Host

  • 102
  • 42
  • 2
Rabbit

Clonality

  • 94
  • 52
Polyclonal

Conjugate

  • 95
  • 10
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Gelsolin antibody is conjugated to AbBy Fluor® 647

Application

  • 114
  • 69
  • 54
  • 52
  • 26
  • 22
  • 17
  • 15
  • 13
  • 12
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

    • 15
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150

    Cross-Reactivity

    Human, Rat

    Predicted Reactivity

    Mouse

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Gelsolin

    Isotype

    IgG
  • Application Notes

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Gelsolin (GSN)

    Alternative Name

    Gelsolin

    Background

    Synonyms: Actin depolymerizing factor, ADF, AGEL, Amyloidosis Finnish type, Brevin, DKFZp313L0718, GSN, GELS_HUMAN, Actin-depolymerizing factor.

    Background: Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin, which appears to account for the difference in relative molecular weights.

    Gene ID

    2934

    UniProt

    P06396

    Pathways

    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
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