GLP2R antibody (PE)

Catalog No. ABIN899011

This Rabbit Polyclonal antibody specifically detects GLP2R in IF (p). It exhibits reactivity toward Human, Cow, Dog and Pig.

Quick Overview for GLP2R antibody (PE) (ABIN899011)

Target: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Reactivity: Human, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLP2R antibody is conjugated to PE

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GLP2R Antibody (PE)

Specificity: Excitation / Emission Wavelengths: 565nm/578nm

Cross-Reactivity: Dog (Canine), Pig (Porcine), Cow (Bovine)

Purification: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human GLP2R

Isotype: IgG

Application Details

Comment:

Excitation / Emission wavelength: 496nm / 578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4 °C for 12 months

Expiry Date: 12 months

Target Details for GLP2R

Target: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Alternative Name: GLP2R

Background: The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq, Jul 2008].

Molecular Weight: 63kDa

Gene ID: 9340

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Feeding Behaviour