GZMK antibody (AA 51-250) (Biotin)

Catalog No. ABIN899686

This Rabbit Polyclonal antibody specifically detects GZMK in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for GZMK antibody (AA 51-250) (Biotin) (ABIN899686)

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GZMK antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Product Details anti-GZMK Antibody (Biotin)

Binding Specificity: AA 51-250

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Granzyme K

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GZMK

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Alternative Name: Granzyme K

Background:

Synonyms: Fragmentin 3, Fragmentin-3, Fragmentin3, GRAK_HUMAN, Granzyme 3, Granzyme K, Granzyme K precursor, Granzyme-3, Granzyme3, GranzymeK, GZMK, NK TRYP 2, NK TRYP2, NK tryptase 2, NK-TRYP-2, NK-tryptase-2, NKTRYP2, Serine protease granzyme 3, TRYP 2, TRYP2, Tryptase II, TryptaseII.

Background: This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008].

Gene ID: 3003