CBS antibody (AA 177-280) (AbBy Fluor® 647)

Catalog No. ABIN900737

The Rabbit Polyclonal anti-CBS antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect CBS in samples from Mouse.

Quick Overview for CBS antibody (AA 177-280) (AbBy Fluor® 647) (ABIN900737)

Target: CBS (Cystathionine-beta-Synthase (CBS))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBS antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CBS Antibody (AbBy Fluor® 647)

Binding Specificity: AA 177-280

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CBS/HIP4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CBS

Target: CBS (Cystathionine-beta-Synthase (CBS))

Alternative Name: CBS

Background:

Synonyms: Beta thionase, Beta-thionase, Cbs, CBS_HUMAN, Cystathionine beta synthase, Cystathionine beta-synthase, HIP 4, HIP4, Methylcysteine synthase, Serine sulfhydrase.

Background: The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010].

Gene ID: 875