IRX3 antibody (AA 401-501) (Biotin)

Catalog No. ABIN903086

The Rabbit Polyclonal anti-IRX3 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect IRX3 in samples from Mouse and Rat.

Quick Overview for IRX3 antibody (AA 401-501) (Biotin) (ABIN903086)

Target: IRX3 (Iroquois Homeobox 3 (IRX3))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRX3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IRX3 Antibody (Biotin)

Binding Specificity: AA 401-501

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Iroquois homeobox protein 3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for IRX3

Target: IRX3 (Iroquois Homeobox 3 (IRX3))

Alternative Name: Iroquois homeobox protein 3

Background:

Synonyms: IRX-1, IRXB1, Iroquois-class homeodomain protein IRX-3, Homeodomain protein IRXB1, Iroquois homeobox protein 3, IRX3, IRX3_HUMAN

Background: Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).

Gene ID: 79191

UniProt: P78415

Pathways: Tube Formation