KLF6 antibody (AbBy Fluor® 350)

Catalog No. ABIN903802

This Rabbit Polyclonal antibody specifically detects KLF6 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for KLF6 antibody (AbBy Fluor® 350) (ABIN903802)

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF6 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB)

Product Details anti-KLF6 Antibody (AbBy Fluor® 350)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLF6

Isotype: IgG

Application Details

Application Notes: IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KLF6

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Alternative Name: Klf6/Pac1

Background:

Synonyms: Kruppel-like factor 6, B cell derived protein 1, BCD1, COPEB, Core promoter element-binding protein, CPBP, GC rich sites binding factor GBF, Krueppel-like factor 6, Proto-oncogene BCD1, Transcription factor Zf9, Zf9, CBA1, DKFZp686N0199, GBF, PAC1, ST12, KLF6_HUMAN.

Background: KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene.

Gene ID: 1316