KLHL20 antibody (AA 13-100) (AbBy Fluor® 488)

Catalog No. ABIN903916

This Rabbit Polyclonal antibody specifically detects KLHL20 in IF (cc) and IF (p). It exhibits reactivity toward Rat.

Quick Overview for KLHL20 antibody (AA 13-100) (AbBy Fluor® 488) (ABIN903916)

Target: KLHL20 (Kelch-Like 20 (KLHL20))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL20 antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-KLHL20 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 13-100

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLHL20

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KLHL20

Target: KLHL20 (Kelch-Like 20 (KLHL20))

Alternative Name: KLHL20

Background:

Synonyms: Kelch like ECT2 interacting protein, Kelch like protein 20, Kelch like protein X, Kelch mot containing protein, Kelch-like ECT2-interacting protein, Kelch-like protein 20, Kelch-like protein X, KHLHX, KLEIP, KLH20CHUMAN, KLHL20, KLHLX, RP3-383J4.3.

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases.

Gene ID: 27252