Lipin 1 antibody (AA 241-340) (AbBy Fluor® 350)

Catalog No. ABIN905058

This anti-Lipin 1 antibody is a Rabbit Polyclonal antibody detecting Lipin 1 in IF (cc) and IF (p). Suitable for Rat and Mouse.

Quick Overview for Lipin 1 antibody (AA 241-340) (AbBy Fluor® 350) (ABIN905058)

Target: Lipin 1 (LPIN1)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipin 1 antibody is conjugated to AbBy Fluor® 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Lipin 1 Antibody (AbBy Fluor® 350)

Binding Specificity: AA 241-340

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Lpin 1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Lipin 1

Target: Lipin 1 (LPIN1)

Alternative Name: Lpin1

Background:

Synonyms: fld, Lipin1, Kiaa0188, mKIAA0188, 4631420P06, Phosphatidate phosphatase LPIN1, Fatty liver dystrophy protein, Lipin-1, Lpin1

Background: Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.

Gene ID: 14245

UniProt: Q91ZP3

Pathways: Monocarboxylic Acid Catabolic Process