Multidrug-Resistance Like Protein 1 antibody (AA 501-600) (AbBy Fluor® 350)

Catalog No. ABIN906944

Product Details anti-Multidrug-Resistance Like Protein 1 Antibody (AbBy Fluor® 350)

Target: Multidrug-Resistance Like Protein 1 (MRP)

Binding Specificity: AA 501-600

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Multidrug-Resistance Like Protein 1 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse MRP1

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Multidrug-Resistance Like Protein 1

Target: Multidrug-Resistance Like Protein 1 (MRP)

Alternative Name: MRP1

Background:

Synonyms: MRP, Mrp1, Mdrap, Abcc1a, Abcc1b, Multidrug resistance-associated protein 1, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter, LTC4 transporter, Abcc1

Background: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

Gene ID: 17250

UniProt: O35379