CCDC19 antibody (AbBy Fluor® 488)

Catalog No. ABIN908009

The Rabbit Polyclonal anti-CCDC19 antibody has been validated for WB. It is suitable to detect CCDC19 in samples from Human, Rat and Mouse.

Quick Overview for CCDC19 antibody (AbBy Fluor® 488) (ABIN908009)

Target: CCDC19 (Coiled-Coil Domain Containing 19 (CCDC19))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC19 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB)

Product Details anti-CCDC19 Antibody (AbBy Fluor® 488)

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC19

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC19

Target: CCDC19 (Coiled-Coil Domain Containing 19 (CCDC19))

Alternative Name: Ccdc19

Background:

Synonyms: Coiled coil domain containing 19, Nasopharyngeal epithelium specic protein 1, NESG1, RP11 190A12.6, CCD19_HUMAN.

Background: CCDC19 is a 466 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1 and, considering the great number of genes, there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson?s, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gene ID: 25790