Nkx2.5/ Cardiac-Specic Homeobox 1 (AA 85-180) antibody (AbBy Fluor® 488)
Quick Overview for Nkx2.5/ Cardiac-Specic Homeobox 1 (AA 85-180) antibody (AbBy Fluor® 488) (ABIN908421)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 85-180
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Cross-Reactivity
- Human, Mouse, Rat
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Predicted Reactivity
- Dog,Cow,Pig,Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from mouse Nkx2.5
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Isotype
- IgG
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anti-Nkx2.5/ Cardiac-Specic Homeobox 1 (AA 85-180) antibody
Reactivity: Human, Mouse, Rat WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
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Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- Nkx2.5/ Cardiac-Specic Homeobox 1
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Alternative Name
- Nkx2.5/Cardiac-specic homeobox 1
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Background
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Synonyms: Csx, Nkx2.5, tinman, Nkx-2.5, Homeobox protein Nkx-2.5, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E, Nkx2-5, Nkx2e
Background: Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.
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Gene ID
- 18091
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UniProt
- P42582
Target
-
