NME5 antibody (AA 81-150) (FITC)

Catalog No. ABIN908525

The Rabbit Polyclonal anti-NME5 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect NME5 in samples from Human.

Quick Overview for NME5 antibody (AA 81-150) (FITC) (ABIN908525)

Target: NME5 (NME/NM23 Family Member 5 (NME5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NME5 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-NME5 Antibody (FITC)

Binding Specificity: AA 81-150

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NME5/IPIA beta

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NME5

Target: NME5 (NME/NM23 Family Member 5 (NME5))

Alternative Name: NME5

Background:

Synonyms: Inhibitor of p53 induced apoptosis beta, IPIA beta, NDK-H 5, NDP kinase homolog 5, NM23 H5, Nm23-M5, NM23H5, Non-metastatic cells 5, protein expressed in nucleoside-diphosphate kinase, Nonmetastatic cells 5, protein expressed in, Nonmetastatic protein 23, homolog 5, Nucleoside diphosphate kinase homolog 5, RSPH23, Testis specic nm23 homolog, NDK5_HUMAN.

Background: NME5 does not seem to have NDK kinase activity but confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. It may play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. NME5 is specifically expressed in testis germinal cells.

Gene ID: 8382

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling