OPRL1 antibody (AA 1-47) (AbBy Fluor® 350)

Catalog No. ABIN908601

This anti-OPRL1 antibody is a Rabbit Polyclonal antibody detecting OPRL1 in WB, IF (cc) and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for OPRL1 antibody (AA 1-47) (AbBy Fluor® 350) (ABIN908601)

Target: OPRL1 (Opiate Receptor-Like 1 (OPRL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRL1 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-OPRL1 Antibody (AbBy Fluor® 350)

Binding Specificity: AA 1-47

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Nociceptin receptor

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for OPRL1

Target: OPRL1 (Opiate Receptor-Like 1 (OPRL1))

Alternative Name: Nociceptin receptor

Background:

Synonyms: KOR3, ORGC, ORL1, Oprl, XOR1, morc, KOR-3, LC132, MOR-C, Nociceptin receptor, K3 opiate receptor, Kappa-type 3 opioid receptor, Orphanin FQ receptor, Oprl1, Oor

Background: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.

Gene ID: 18389

UniProt: P35377