PRODH antibody (AA 141-240) (AbBy Fluor® 350)

Catalog No. ABIN912206

The Rabbit Polyclonal anti-PRODH antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect PRODH in samples from Mouse and Rat.

Quick Overview for PRODH antibody (AA 141-240) (AbBy Fluor® 350) (ABIN912206)

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRODH antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PRODH Antibody (AbBy Fluor® 350)

Binding Specificity: AA 141-240

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PRODH

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PRODH

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Alternative Name: PRODH

Background:

Synonyms: POX, PIG6, HSPOX2, PRODH1, PRODH2, TP53I6, Proline dehydrogenase 1, mitochondrial, Proline oxidase, Proline oxidase 2, p53-induced gene 6 protein, PRODH, POX2

Background: Proline oxidase catalyzes the conversion of proline to pyrroline-5-carboxylate, or P5C during the degradation of the amino acid Proline. Defects in PRODH are the cause of hyperprolinemia type 1, a disorder characterized by elevated serum proline levels. Defective PRODH may be involved in the psychiatric and behavioral phenotypes associated with the 22q11 velocardiofacial and DiGeorge syndrome and may be associated with susceptibility to schizophrenia 4 (SCZD4).

Gene ID: 5625

UniProt: O43272

Pathways: Response to Water Deprivation, Monocarboxylic Acid Catabolic Process