ROBO2 antibody (AA 144-220) (Biotin)

Catalog No. ABIN913880

The Rabbit Polyclonal anti-ROBO2 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect ROBO2 in samples from Mouse.

Quick Overview for ROBO2 antibody (AA 144-220) (Biotin) (ABIN913880)

Target: ROBO2 (Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROBO2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ROBO2 Antibody (Biotin)

Binding Specificity: AA 144-220

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Robo2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ROBO2

Target: ROBO2 (Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2))

Alternative Name: Robo2

Background:

Synonyms: lea, Robo 2, ROBO2, ROBO2_HUMAN, Roundabout 2, Roundabout homolog 2, roundabout, axon guidance receptor, homolog 2 Drosophila, Roundabout2, SAX 3,SAX3.

Background: Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development.Involvement in disease:Defects in ROBO2 are the cause of vesicoureteral reflux type 2 (VUR2) . VUR is a complex, genetically heterogeneous developmental disorder characterized by the retrograde flow of urine from the bladder into the ureter and is associated with reflux nephropathy, the cause of 15 % of end-stage renal disease in children and young adults.

Gene ID: 6092

Pathways: Regulation of Cell Size