Retinoid X Receptor beta antibody (AbBy Fluor® 647)
Quick Overview for Retinoid X Receptor beta antibody (AbBy Fluor® 647) (ABIN914136)
Target
See all Retinoid X Receptor beta (RXRB) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human RXR beta
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Isotype
- IgG
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Application Notes
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IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))
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Alternative Name
- Rxr beta
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Background
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Synonyms: Retinoid X Receptor beta, DAUD I6, DAUDI6, H 2RIIBP, H2RIIBP, MHC class I promoter binding protein, NR2B2, RCoR 1, RCoR1, Retinoic acid receptor RXR beta, RXR beta, RXRB, RXRbeta.
Background: Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).
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Gene ID
- 6257
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Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
Target
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