SMYD2A antibody (AbBy Fluor® 555)

Catalog No. ABIN915892

This Rabbit Polyclonal antibody specifically detects SMYD2A in IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SMYD2A antibody (AbBy Fluor® 555) (ABIN915892)

Target: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMYD2A antibody is conjugated to AbBy Fluor® 555

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SMYD2A Antibody (AbBy Fluor® 555)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SMYD2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for SMYD2A

Target: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Alternative Name: SMYD2

Background:

Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.

Synonyms: HSKM B, HSKM-B, HSKMB, Histone methyltransferase SMYD2, HSKM-B, Lysine N-methyltransferase 3C, MGC119305, N lysine methyltransferase SMYD2, N-lysine methyltransferase SMYD2, SET and MYND domain containing 2, SET and MYND domain containing protein 2, SET and MYND domain-containing protein 2, Smyd2, SMYD2_HUMAN, Zinc finger MYND domain containing 14, ZMYND14.

Gene ID: 56950