TFAP2C antibody (AA 2-100) (AbBy Fluor® 647)

Catalog No. ABIN917378

The Rabbit Polyclonal anti-TFAP2C antibody is suitable to detect TFAP2C in samples from Mouse and Rat. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for TFAP2C antibody (AA 2-100) (AbBy Fluor® 647) (ABIN917378)

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAP2C antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TFAP2C Antibody (AbBy Fluor® 647)

Binding Specificity: AA 2-100

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TFAP2C

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TFAP2C

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Alternative Name: AP2 gamma

Background:

Synonyms: ERF1, TFAP2G, hAP-2g, AP2-GAMMA, Transcription factor AP-2 gamma, Activating enhancer-binding protein 2 gamma, Transcription factor ERF-1, TFAP2C

Background: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Gene ID: 7022

UniProt: Q92754

Pathways: Stem Cell Maintenance