THAP1 antibody (AA 121-213) (Biotin)

Catalog No. ABIN917542

This Rabbit Polyclonal antibody specifically detects THAP1 in ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for THAP1 antibody (AA 121-213) (Biotin) (ABIN917542)

Target: THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THAP1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-THAP1 Antibody (Biotin)

Binding Specificity: AA 121-213

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human THAP1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for THAP1

Target: THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))

Alternative Name: THAP1

Background:

Synonyms: Nuclear proapoptotic factor, THAP 1, THAP domain containing apoptosis associated protein 1, THAP domain containing protein 1, THAP domain protein 1, THAP1_HUMAN.

Background: THAP1 contains a THAP domain, a zinc-dependent DNA-binding domain. It colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies and is a pro-apoptopic protein that potentiates both serum-withdrawal and TNF-induced apoptosis. It is a physiologic regulator of endothelial cell proliferation and cell-cycle progression, two essential processes for angiogenesis.

Gene ID: 55145