TSPYL5 antibody (AA 251-350) (Cy3)

Catalog No. ABIN918868

This Rabbit Polyclonal antibody specifically detects TSPYL5 in FACS, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for TSPYL5 antibody (AA 251-350) (Cy3) (ABIN918868)

Target: TSPYL5 (TSPY-Like 5 (TSPYL5))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPYL5 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TSPYL5 Antibody (Cy3)

Binding Specificity: AA 251-350

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSPYL5

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TSPYL5

Target: TSPYL5 (TSPY-Like 5 (TSPYL5))

Alternative Name: TSPYL5

Background:

Synonyms: Testis-specific Y-encoded-like protein 5, TSPY-like protein 5, TSPYL5, KIAA1750

Background: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination, the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.

Gene ID: 85453

UniProt: Q86VY4