WRAP53 antibody (AA 285-390) (HRP)

Catalog No. ABIN919951

This Rabbit Polyclonal antibody specifically detects WRAP53 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse and Rat.

Quick Overview for WRAP53 antibody (AA 285-390) (HRP) (ABIN919951)

Target: WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WRAP53 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-WRAP53 Antibody (HRP)

Binding Specificity: AA 285-390

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WDR79/TCAB1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for WRAP53

Target: WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))

Alternative Name: TCAB1

Background:

Synonyms: FLJ10385, TCAB1, telomerase Cajal Body protein 1, WD repeat containing protein 79, WRAP53, WDR79/TCAB1, WAP53_HUMAN.

Background: WDR79 contains six WD (tryptophan-aspartate) repeat domains found in a number of proteins that function as adaptor molecules in signal transduction and cytoskeletal organization. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. The function of the WDR79 protein has not been characterized, however significant and consistent single nucleotide polymorphisms in the WDR79 gene have been found to be associated with ER negative breast cancer.

Gene ID: 3135

UniProt: Q9BUR4

Pathways: Telomere Maintenance