F11R antibody

Catalog No. ABIN920705

The Rat Monoclonal anti-F11R antibody is suitable to detect F11R in samples from Mouse. It has been validated for FACS, IF and IA.

Quick Overview for F11R antibody (ABIN920705)

Target: F11R (F11 Receptor (F11R))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This F11R antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunoassay (IA)

Clone: BV12

Product Details anti-F11R Antibody

Specificity: Reacts with JAM-1.

Sterility: 0.2 μm filtered

Isotype: IgG

Application Details

Application Notes: Flow cytometry: Use at a 1:10 dilution. Immunofluorescence: (fixed cells)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 mL of 100 µg/mL 0.2 µm filtered antibody solution in PBS containing 0.1% protein stabilizer and 0.02% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: JAM-1

Background: Junctional adhesion molecule-1 (JAM-1) is a cell adhesion molecule (CAM). JAM-1 is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular juctions of endothelial cells and epithelial cells. JAM-1 belongs together with JAM-2 and JAM-3 to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It co-distributes with other tight junction components such as ZO-1, 7H6 antigen, cingulin and occludin. In humans JAM-1 plays a role in platelet aggregation, secretion, adhesion and spreading. Synonyms: Platelet F11-Receptor (F11R)

Pathways: Cell-Cell Junction Organization