MAX antibody (Middle Region)

Catalog No. ABIN925892

The Rabbit Polyclonal anti-MAX antibody has been validated for WB. It is suitable to detect MAX in samples from Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken and Xenopus laevis.

Quick Overview for MAX antibody (Middle Region) (ABIN925892)

Target: MAX (MYC Associated Factor X (MAX))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAX Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Mouse (Murine), Dog (Canine), Rat (Rattus), Cow (Bovine), Frog, Chicken, Zebrafish (Brachydanio rerio)

Immunogen: MAX antibody was raised in rabbit using the middle region of MAX as the immunogen

Application Details

Application Notes: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

MAX Blocking Peptide, (ABIN5614684), is also available for use as a blocking control in assays to test for specificity of this MAX antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for MAX

Target: MAX (MYC Associated Factor X (MAX))

Alternative Name: MAX

Background: MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Synonyms: Polyclonal MAX antibody, Anti-MAX antibody, MYC associated factor X antibody.

Pathways: Mitotic G1-G1/S Phases