MafF antibody (N-Term)

Catalog No. ABIN925912

This Rabbit Polyclonal antibody specifically detects MafF in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Drosophila melanogaster and Chicken.

Quick Overview for MafF antibody (N-Term) (ABIN925912)

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Drosophila melanogaster, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MafF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MafF Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Fruit Fly (Drosophila melanogaster), Zebrafish (Brachydanio rerio), Chicken

Immunogen: MAFF antibody was raised in rabbit using the N terminal of MAFF as the immunogen

Application Details

Application Notes: WB: 5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

MAFF Blocking Peptide, (ABIN5614626), is also available for use as a blocking control in assays to test for specificity of this MAFF antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for MafF

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Alternative Name: MAFF

Background: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response. Synonyms: Polyclonal MAFF antibody, Anti-MAFF antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog F, avian antibody.

Pathways: Myometrial Relaxation and Contraction