NR2F2 antibody (N-Term)

Catalog No. ABIN925921

This Rabbit Polyclonal antibody specifically detects NR2F2 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken and Xenopus laevis.

Quick Overview for NR2F2 antibody (N-Term) (ABIN925921)

Target: NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR2F2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NR2F2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Chicken, Zebrafish (Brachydanio rerio), Frog

Immunogen: NR2 F2 antibody was raised in rabbit using the N terminal of NR2 2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

NR2F2 Blocking Peptide, (ABIN5615051), is also available for use as a blocking control in assays to test for specificity of this NR2F2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for NR2F2

Target: NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))

Alternative Name: NR2F2

Background: NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation. Synonyms: Polyclonal NR2F2 antibody, Anti-NR2F2 antibody, nuclear receptor subfamily 2, group F, member 2 antibody, ARP1 antibody, COUP-TFII antibody, COUPTFB antibody, MGC117452 antibody, SVP40 antibody, TFCOUP2 antibody.

Pathways: Steroid Hormone Mediated Signaling Pathway