RNASEL antibody (C-Term)

Catalog No. ABIN926018

The Rabbit Polyclonal anti-RNASEL antibody is suitable to detect RNASEL in samples from Human, Pig, Cow and Dog. It has been validated for WB.

Quick Overview for RNASEL antibody (C-Term) (ABIN926018)

Target: RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))

Reactivity: Human, Pig, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASEL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RNASEL Antibody

Binding Specificity: C-Term

Cross-Reactivity: Pig (Porcine), Dog (Canine), Cow (Bovine)

Immunogen: RNASEL antibody was raised in rabbit using the C terminal of RNASEL as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

RNASEL Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this RNASEL antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RNASEL

Target: RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))

Alternative Name: RNASEL

Background: This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. Synonyms: Polyclonal RNASEL antibody, Anti-RNASEL antibody, ribonuclease L, 2',5'-oligoisoadenylate synthetase-dependent antibody.

Pathways: Hepatitis C