He-Dcyd antibody
Reactivity: Chemical
ELISA
Host: Goat
Polyclonal
unconjugated
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- Target
- He-Dcyd
- Reactivity
- Chemical
- Host
- Goat
- Clonality
- Polyclonal
- Application
- ELISA
- Immunogen
- He-dcyd antibody was raised in Goat using Heptanone-etheno-2?-Deoxycytidine as the immunogen.
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- Application Notes
- ELISA: >1:10,000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- liquid form with 0.01 % Thimerosal and 0.1 % Sodium Azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Target
- He-Dcyd
- Target Type
- Chemical
- Background
- Heptanone-etheno-2?-Deoxycytidine is a free-radical modified DNA adduct that may serve as a marker for cancer. HedC has been shown to be highly mutagenic in both bacterial and human cells. When an HepsilondC adduct was placed in a plasmid that was replicated in both bacterial and human cells, it was able to completely block DNA replication in the bacteria and only small fractions of progeny were detected in the human cells suggesting that HepsilondC is a very strong block to DNA synthesis. Additionally, HepsilondC also strongly miscodes when bypassed in bacterial and human cell systems resulting in a miscoding frequency of about 45 % and 90 % respectively. . Synonyms: Polyclonal He-dcyd antibody, Anti-He-dcyd antibody, Heptanone-etheno-2?-Deoxycytidine antibody, Heptanone etheno 2 Deoxycytidine antibody, Hedcyd antibody, He dcyd antibody.
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