IDS antibody (N-Term)
Quick Overview for IDS antibody (N-Term) (ABIN926632)
Target
See all IDS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Purification
- Purified
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Immunogen
- IDS antibody was raised in rabbit using the N terminal of IDS as the immunogen
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Application Notes
- Optimal conditions should be determined by the investigator.
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Comment
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IDS Blocking Peptide, (ABIN5614136), is also available for use as a blocking control in assays to test for specificity of this IDS antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- IDS (Iduronate 2-Sulfatase (IDS))
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Alternative Name
- IDS
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Background
- Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described. Synonyms: Polyclonal IDS antibody, Anti-IDS antibody, iduronate 2-sulfatase antibody, MPS2 antibody, SIDS antibody.
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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