KLRC1 antibody (C-Term)

Catalog No. ABIN926709

This anti-KLRC1 antibody is a Rabbit Polyclonal antibody detecting KLRC1 in WB. Suitable for Human.

Quick Overview for KLRC1 antibody (C-Term) (ABIN926709)

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLRC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLRC1 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: KLRC1 antibody was raised in rabbit using the C terminal of KLRC1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

KLRC1 Blocking Peptide, (ABIN5614393), is also available for use as a blocking control in assays to test for specificity of this KLRC1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for KLRC1

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Alternative Name: KLRC1

Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. Synonyms: Polyclonal KLRC1 antibody, Anti-KLRC1 antibody, killer cell lectin-like receptor subfamily C, member 1 antibody, CD159A antibody, MGC13374 antibody, MGC59791 antibody, NKG2 antibody, NKG2A antibody.