GBA antibody (C-Term)

Catalog No. ABIN926718

This anti-GBA antibody is a Rabbit Polyclonal antibody detecting GBA in WB. Suitable for Human.

Quick Overview for GBA antibody (C-Term) (ABIN926718)

Target: GBA (Glucosidase, Beta, Acid (GBA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GBA Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: GBA antibody was raised in rabbit using the C terminal of GBA as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

GBA Blocking Peptide, (ABIN936300), is also available for use as a blocking control in assays to test for specificity of this GBA antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Alternative Name: GBA

Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. Synonyms: Polyclonal GBA antibody, Anti-GBA antibody, glucosidase, beta, acid antibody, GBA1 antibody, GCB antibody, GLUC antibody.

Pathways: Cellular Glucan Metabolic Process