RPL7 antibody (C-Term)

Catalog No. ABIN926766

Product Details anti-RPL7 Antibody

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL7 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: RPL7 antibody was raised in rabbit using the C terminal of RPL7 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

RPL7 Blocking Peptide, catalog no. 33R-10269, is also available for use as a blocking control in assays to test for specificity of this RPL7 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RPL7

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Alternative Name: RPL7 (RPL7 Products)

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Synonyms: Polyclonal RPL7 antibody, Anti-RPL7 antibody, ribosomal protein L7 antibody, MGC117326 antibody, humL7-1 antibody.