Histone 3 antibody (N-Term)

Catalog No. ABIN926860

This Rabbit Polyclonal antibody specifically detects Histone 3 in WB. It exhibits reactivity toward Human.

Quick Overview for Histone 3 antibody (N-Term) (ABIN926860)

Target: Histone 3 (H3) (Histone H3 (H3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Histone 3 Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: HIST3 H3 antibody was raised in rabbit using the N terminal of HIST3 3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HIST3H3 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this HIST3H3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Histone 3

Target: Histone 3 (H3) (Histone H3 (H3))

Alternative Name: HIST3H3

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. Synonyms: Polyclonal HIST3H3 antibody, Anti-HIST3H3 antibody, histone cluster 3, H3 antibody, H3.4 antibody, H3/g antibody, H3FT antibody, H3t antibody, MGC126886 antibody, MGC126888 antibody.