TRADD antibody (Middle Region)

Catalog No. ABIN926870

The Rabbit Polyclonal anti-TRADD antibody has been validated for WB. It is suitable to detect TRADD in samples from Human and Dog.

Quick Overview for TRADD antibody (Middle Region) (ABIN926870)

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRADD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRADD Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Dog (Canine)

Purification: Purified

Immunogen: TRADD antibody was raised in rabbit using the middle region of TRADD as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TRADD Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this TRADD antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TRADD

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Alternative Name: TRADD

Background: TRADD is the adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. Synonyms: Polyclonal TRADD antibody, Anti-TRADD antibody, TNFRSF1A-associated via death domain antibody, Hs.89862 antibody, MGC11078 antibody.

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C