BIRC7 antibody (Middle Region)

Catalog No. ABIN926876

The Rabbit Polyclonal anti-BIRC7 antibody has been validated for WB. It is suitable to detect BIRC7 in samples from Human.

Quick Overview for BIRC7 antibody (Middle Region) (ABIN926876)

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BIRC7 Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: BIRC7 antibody was raised in rabbit using the middle region of BIRC7 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

BIRC7 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this BIRC7 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for BIRC7

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Alternative Name: BIRC7

Background: BIRC7 protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Synonyms: Polyclonal BIRC7 antibody, Anti-BIRC7 antibody, baculoviral IAP repeat-containing 7, livin antibody, KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody.