RIPK2 antibody (Middle Region)

Catalog No. ABIN926883

This anti-RIPK2 antibody is a Rabbit Polyclonal antibody detecting RIPK2 in WB. Suitable for Human, Mouse, Rat, Cow, Dog and Chicken.

Quick Overview for RIPK2 antibody (Middle Region) (ABIN926883)

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIPK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RIPK2 Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Chicken

Purification: Purified

Immunogen: RIPK2 antibody was raised in rabbit using the middle region of RIPK2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RIPK2 Blocking Peptide, catalog no. 33R-5381, is also available for use as a blocking control in assays to test for specificity of this RIPK2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RIPK2

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Alternative Name: RIPK2

Background: RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. Synonyms: Polyclonal RIPK2 antibody, Anti-RIPK2 antibody, receptor-interacting serine-threonine kinase 2 antibody, CARD3 antibody, CARDIAK antibody, CCK antibody, GIG30 antibody, RICK antibody, RIP2 antibody.

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades