Cyclin T1 antibody (N-Term)

Catalog No. ABIN926896

This Rabbit Polyclonal antibody specifically detects Cyclin T1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Pig, Xenopus laevis and Zebrafish (Danio rerio).

Quick Overview for Cyclin T1 antibody (N-Term) (ABIN926896)

Target: Cyclin T1 (CCNT1)

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Xenopus laevis, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin T1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin T1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Frog, Pig (Porcine), Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: CCNT1 antibody was raised in rabbit using the N terminal of CCNT1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CCNT1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CCNT1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Cyclin T1

Target: Cyclin T1 (CCNT1)

Alternative Name: CCNT1

Background: CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. Synonyms: Polyclonal CCNT1 antibody, Anti-CCNT1 antibody, cyclin T1 antibody, CCNT antibody, CYCT1 antibody.