CDK1 antibody (C-Term)

Catalog No. ABIN926898

This anti-CDK1 antibody is a Rabbit Polyclonal antibody detecting CDK1 in WB and IHC. Suitable for Human.

Quick Overview for CDK1 antibody (C-Term) (ABIN926898)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CDK1 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: CDC2 antibody was raised in rabbit using the C terminal of CDC2 as the immunogen

Application Details

Application Notes: WB: 0.1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CDC2 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CDC2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Alternative Name: CDC2

Background: The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Synonyms: Polyclonal CDC2 antibody, Anti-CDC2 antibody, cell division cycle 2, G1 to S and G2 to M antibody, CDC28A antibody, CDK1 antibody, DKFZp686L20222 antibody, MGC111195 antibody.

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA