DOK2 antibody (C-Term)

Catalog No. ABIN926941

This Rabbit Polyclonal antibody specifically detects DOK2 in WB. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for DOK2 antibody (C-Term) (ABIN926941)

Target: DOK2

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DOK2 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine)

Purification: Purified

Immunogen: DOK2 antibody was raised in rabbit using the C terminal of DOK2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

DOK2 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this DOK2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for DOK2

Target: DOK2

Alternative Name: DOK2

Background: DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK2 binds p120 (RasGAP) from CML cells.The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. Synonyms: Polyclonal DOK2 antibody, Anti-DOK2 antibody, docking protein 2, 56kDa antibody.