STXBP1 antibody (Middle Region)

Catalog No. ABIN926990

The Rabbit Polyclonal anti-STXBP1 antibody has been validated for WB. It is suitable to detect STXBP1 in samples from Human, Mouse, Rat, Cow, Chicken, Xenopus laevis, Zebrafish (Danio rerio).

Quick Overview for STXBP1 antibody (Middle Region) (ABIN926990)

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Reactivity: Human, Mouse, Rat, Cow, Chicken, Xenopus laevis, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STXBP1 Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Chicken, Frog, Cow (Bovine), Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: STXBP1 antibody was raised in rabbit using the middle region of STXBP1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

STXBP1 Blocking Peptide, catalog no. 33R-9269, is also available for use as a blocking control in assays to test for specificity of this STXBP1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for STXBP1

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Alternative Name: STXBP1

Background: STXBP1 belongs to the STXBP/unc-18/SEC1 family. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. The protein is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4. Synonyms: Polyclonal STXBP1 antibody, Anti-STXBP1 antibody, syntaxin binding protein 1 antibody, MUNC18-1 antibody, UNC18 antibody, hUNC18 antibody, rbSec1 antibody.

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport