ARNT antibody (C-Term)

Catalog No. ABIN927314

The Rabbit Polyclonal anti-ARNT antibody has been validated for WB. It is suitable to detect ARNT in samples from Human and Rat.

Quick Overview for ARNT antibody (C-Term) (ABIN927314)

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARNT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARNT Antibody

Binding Specificity: C-Term

Cross-Reactivity: Rat (Rattus)

Purification: Purified

Immunogen: Arnt antibody was raised in rabbit using the C terminal of Arnt as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

Arnt Blocking Peptide, (ABIN5612165), is also available for use as a blocking control in assays to test for specificity of this Arnt antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for ARNT

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Alternative Name: Arnt

Background: Arnt is required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia. Synonyms: Polyclonal Arnt antibody, Anti-Arnt antibody, aryl hydrocarbon receptor nuclear translocator antibody, Arnt1 antibody, Arnt antibody.

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect