ZBTB33 antibody (N-Term)

Catalog No. ABIN927742

This Rabbit Polyclonal antibody specifically detects ZBTB33 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Chicken and Xenopus laevis.

Quick Overview for ZBTB33 antibody (N-Term) (ABIN927742)

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Reactivity: Human, Mouse, Rat, Dog, Cow, Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB33 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZBTB33 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Chicken, Frog

Purification: Purified

Immunogen: ZBTB33 antibody was raised in rabbit using the N terminal of ZBTB33 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

ZBTB33 Blocking Peptide, (ABIN5617076), is also available for use as a blocking control in assays to test for specificity of this ZBTB33 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for ZBTB33

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Alternative Name: ZBTB33

Background: ZBTB33 is a transcriptional regulator with bimodal DNA-binding specificity. ZBTB33 binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. ZBTB33 recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway. It may also activate transcription of a subset of target genes by the recruitment of CTNND2. Synonyms: Polyclonal ZBTB33 antibody, Anti-ZBTB33 antibody, zinc finger and BTB domain containing 33 antibody.