BCL11A antibody (N-Term)

Catalog No. ABIN927793

This Rabbit Polyclonal antibody specifically detects BCL11A in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken and Xenopus laevis.

Quick Overview for BCL11A antibody (N-Term) (ABIN927793)

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL11A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCL11A Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Zebrafish (Brachydanio rerio), Cow (Bovine), Dog (Canine), Chicken, Frog

Purification: Purified

Immunogen: BCL11 A antibody was raised in rabbit using the N terminal of BCL11 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

BCL11A Blocking Peptide, (ABIN5612298), is also available for use as a blocking control in assays to test for specificity of this BCL11A antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for BCL11A

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Alternative Name: BCL11A

Background: BCL11A Is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Synonyms: Polyclonal BCL11A antibody, Anti-BCL11A antibody, B-cell CLL/lymphoma 11A, zinc finger protein antibody, BCL11A-L antibody, BCL11A-S antibody, BCL11A-XL antibody, CTIP1 antibody, EVI9 antibody, FLJ10173 antibody, FLJ34997 antibody, HBFQTL5 antibody, KIAA1809 antibody.

Pathways: Regulation of Cell Size