BCL11A antibody (C-Term)

Catalog No. ABIN927829

This Rabbit Polyclonal antibody specifically detects BCL11A in WB. It exhibits reactivity toward Human.

Quick Overview for BCL11A antibody (C-Term) (ABIN927829)

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL11A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCL11A Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: BCL11 A antibody was raised in rabbit using the C terminal of BCL11 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

BCL11A Blocking Peptide, (ABIN935999), is also available for use as a blocking control in assays to test for specificity of this BCL11A antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for BCL11A

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Alternative Name: BCL11A

Background: BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Synonyms: Polyclonal BCL11A antibody, Anti-BCL11A antibody, B-cell CLL/lymphoma 11A, zinc finger protein antibody, BCL11A-L antibody, BCL11A-S antibody, BCL11A-XL antibody, CTIP1 antibody, EVI9 antibody, FLJ10173 antibody, FLJ34997 antibody, HBFQTL5 antibody, KIAA1809 antibody, ZNF856 antibody.

Pathways: Regulation of Cell Size