KCC2 antibody (N-Term)

Catalog No. ABIN928045

This Rabbit Polyclonal antibody specifically detects KCC2 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for KCC2 antibody (N-Term) (ABIN928045)

Target: KCC2 (SLC12A5) (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 5 (SLC12A5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCC2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Slc12 a5 antibody was raised in rabbit using the N terminal of Slc12 5 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Slc12a5 Blocking Peptide, (ABIN5616178), is also available for use as a blocking control in assays to test for specificity of this Slc12a5 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for KCC2

Target: KCC2 (SLC12A5) (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 5 (SLC12A5))

Alternative Name: Slc12a5

Background: K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium  potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a  net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Synonyms: Polyclonal Slc12a5 antibody, Anti-Slc12a5 antibody, solute carrier family 12, member 5 antibody, KCC2 antibody, mKIAA1176 antibody.