PA2G4 antibody (C-Term)

Catalog No. ABIN928175

The Rabbit Polyclonal anti-PA2G4 antibody has been validated for WB. It is suitable to detect PA2G4 in samples from Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio) and Xenopus laevis.

Quick Overview for PA2G4 antibody (C-Term) (ABIN928175)

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PA2G4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PA2G4 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Frog, Cow (Bovine), Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: PA2 G4 antibody was raised in rabbit using the C terminal of PA2 4 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

PA2G4 Blocking Peptide, (ABIN5615180), is also available for use as a blocking control in assays to test for specificity of this PA2G4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for PA2G4

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Alternative Name: PA2G4

Background: PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Synonyms: Polyclonal PA2G4 antibody, Anti-PA2G4 antibody, proliferation-associated 2G4, 38kDa antibody, EBP1 antibody, HG4-1 antibody, p38-2G4 antibody.

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades