GNPTAB antibody (N-Term)

Catalog No. ABIN928289

The Rabbit Polyclonal anti-GNPTAB antibody is suitable to detect GNPTAB in samples from Human. It has been validated for WB.

Quick Overview for GNPTAB antibody (N-Term) (ABIN928289)

Target: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNPTAB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GNPTAB Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: GNPTAB antibody was raised in rabbit using the N terminal of GNPTAB as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

GNPTAB Blocking Peptide, (ABIN938417), is also available for use as a blocking control in assays to test for specificity of this GNPTAB antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for GNPTAB

Target: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Alternative Name: GNPTAB

Background: This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Synonyms: Polyclonal GNPTAB antibody, Anti-GNPTAB antibody, N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits antibody, DKFZp762B226 antibody, GNPTA antibody, ICD antibody, KIAA1208 antibody, MGC4170 antibody.